翻訳と辞書 Words near each other ・ Ubinsky District ・ Ubin–Khatib Important Bird Area ・ UBiome ・ Ubique ・ Ubique (company) ・ Ubique (poem) ・ Ubiquilin 4 ・ Ubiquinol ・ Ubiquinol oxidase ・ Ubiquinol oxidase (H+-transporting) ・ Ubiquinone reductase ・ Ubiquitarians ・ Ubiquiti Networks ・ Ubiquitin ・ Ubiquitin A-52 residue ribosomal protein fusion product 1 ・ Ubiquitin B ・ Ubiquitin C ・ Ubiquitin C-terminal hydrolase ・ Ubiquitin carboxy-terminal hydrolase L1 ・ Ubiquitin carboxyl-terminal hydrolase L5 ・ Ubiquitin D ・ Ubiquitin ligase ・ Ubiquitin-activating enzyme ・ Ubiquitin-binding domains ・ Ubiquitin-conjugating enzyme ・ Ubiquitin-interacting motif ・ Ubiquitinyl hydrolase 1 ・ Ubiquitin—calmodulin ligase ・ Ubiquitous commerce ・ Ubiquitous Communicator Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Ubiquitin B ： ウィキペディア英語版 Ubiquitin B Ubiquitin is a protein that in humans is encoded by the ''UBB'' gene. == Function == Ubiquitin is one of the most conserved proteins known in eukaryotic organisms. Ubiquitin is required for ATP-dependent, non-lysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein (UBB+1) has been noticed in patients with Alzheimer's disease, Down syndrome, other tauopathies (e.g. Pick's disease) and polyglutamine disease (e.g. Huntington's disease).〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7314 )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Ubiquitin B」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.